We are now hiring a Ph.D-level biochemist/protein chemist/enzymologist to join our structure biology group.

Key Responsibilities:

• Work closely with disease biology, Medichem and HTS project teams for integrated efforts for high quality and high efficiency protein production and protein characterization, structure determination, to provide key insights into protein-function analysis of protein targets and protein-small molecule complexes.
• Work closely with Data Science and other drug discovery functions for novel drug target identification and validation, and structure-function elucidation through dry and wet lab techniques. 

Main requirements:

• Ph.D. degree in the fields of Biochemistry and Biophysics, Molecular Biology, Structure Enzymology, Immunology, or any related fields.
• In-depth knowledge of protein biochemistry and biophysics is a must. 
• Familiar with drug discovery processes in disease areas, including anti-bacterial, anti-viral and oncology is a plus.
• Experience with molecular modeling, protein structure determination software, such as Phenix, COOT, CCP4, RELION, ability to use common structural visualization tools, including Pymol, for sharing structural information and structure analysis, is a plus.
• Proficiency in various chromatography protein purification methods and protein characterization techniques. Hands on experiences with CD, DLS, MST and SPR protein analytic methods is a must.
• Have extensive hands-on experiences in molecular biology techniques, recombinant protein production in various expression systems.  
• Experience with enzymatic kinetic studies and immunological assay, such as ELISA, is a plus.
• Hands-on experience in structure determination techniques, including x-ray crystallography, Cyro-EM or NMR is preferred. 
• Have meticulous and rigorous altitude towards foundation of the science hypothesis and proven of hypothesis through carefully designed experiments.
• Be result-oriented, be able to independently design and execute the research and experimental plans for protein drug target characterization projects.
• A good team-player, willing to collaborate, actively communicate, eagerly learn new technologies and share knowledge.