加入我们

GHDDI正在迅速成长,拥有杰出药物研发能力的人才团队是中心发展的基石。我们欢迎有突出能力的科研人员、有经验的管理者及专业运营人员加入我们。GHDDI为积极主动、有创造力和创业精神的员工提供多元化、充满活力的工作环境以及良好的发展机会。我们的员工认同GHDDI的使命,分享共同的愿景,携手致力科学和人类健康事业的发展。

有求职意向者请将简历发送至:career@ghddi.org.
各级别传染病学家,疾病生物学  

Key Responsibilities

  • The duties of this position will involve supporting and/or leading a multidisciplinary team to develop innovative therapeutic drugs for infectious diseases such viral infections caused by HBV, DENV and ZIKV, SARS-CoV-2, et al.

  • The candidate will use in vitro HTS assays to identify innovative drug hits and animal models to evaluate the efficacy of hits and the mechanism of action of these hits.

  • The candidate will work both independently and collaboratively in a matrixed environment to design, execute, interpret and communicate biological studies for one or more projects utilizing good scientific judgment and strong team skills.


Minimum Requirements

  • M.S. or Ph.D. in appropriate discipline required (e.g., biochemistry, virology, immunology, cell biology, molecular biology).

  • 2-8 years’ experience (industry experience preferred).

  • Excellent verbal and written communication/Presentation skills, in addition to excellent organizational skills.

  • Expertise in current technology practices in viral immunology and molecular biology is preferred.

  • Experience in protein expression, purification and characterization is preferred

  • Experience in enzymatic and cellular assay establishment and optimization is Preferred.

  • Experience in viral culture, HBV, DENV and ZIKV, SARS-CoV-2 manipulation Is Preferred.

  • Hands-on expertise in screening assay development to provide optimal HTS system for in vitro drug screening.

  • Ability to independently design experiments, make detailed observations, analyze data, interpret results and deliver timely results.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

(高级)研究助理,生物化学/蛋白质化学  

Key Responsibilities

  • Apply expertise in protein expression/production, biochemistry/biophysical characterization, protein structure-function elucidation to aid the drug-discovery process at GHDDI.

  • Work closely with Structure Biology Team members for integrated efforts for high quality and high efficiency protein production and protein characterization, structure determination research efforts, to provide key insights protein-functions analysis.


Minimum Requirements

  • MS degree with minimum of 3-5-year post-graduate working experience in the fields of Biochemistry and Biophysics, Structural Biology, Molecular Biology or any related fields.

  • Have extensive hands-on experiences in molecular biology techniques, recombinant protein production in various expression systems.

  • Proficient in various chromatography protein purification methods and protein characterization techniques. Hands on experiences with CD, DLS, MST and SPR protein analytic methods is a plus.

  • In-depth knowledge on protein biochemistry and biophysics is preferred.

  • Familiarity with structure determination techniques, including x-ray crystallography, cyro-EM or NMR is a plus.

  • Be result-oriented, be able to independently design and execute the plans for protein construct design, expression and characterization.

  • A good team-player, willing to collaborate, actively communicate, eagerly learn new technologies and share knowledge.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

(助理)研究员,生物化学/蛋白质化学  

Key Responsibilities

  • Apply different biochemical and biophysical characterization techniques to support the various structure biology functions, including protein expression/production and protein purification, assay development, protein-small molecule and protein-protein interaction through 3D-structural determination or other biophysical techniques.

  • Work closely with Structure Biology Team members for integrated efforts for high quality and high efficiency protein production and protein characterization, structure determination research efforts, to provide key insights protein-functions analysis.


Minimum Requirements

  • Ph.D. degree in the fields of Biochemistry and Biophysics, Structural Biology, Molecular Biology or any related fields.

  • Have extensive hands-on experiences in molecular biology techniques, recombinant protein production in various expression systems.

  • Proficiency in various chromatography protein purification methods and protein characterization techniques. Hands on experiences with CD, DLS, MST and SPR protein analytic methods is a must.

  • Experience with enzymatic kinetic studies and immunological assay, such as ELISA, is a plus.

  • In-depth knowledge on protein biochemistry and biophysics is a must.

  • Hands-on experiences in structure determination techniques, including x-ray crystallography, cyro-EM or NMR is preferred.

  • Experience with molecular modeling, protein structure determination software, such as Phenix, COOT, CCP4, RELION, ability to use common structural visualization tools, including Pymol, for sharing structural information and structure analysis, is a plus.

  • Be result-oriented, be able to independently design and execute the plans for protein construct design, expression and characterization.

  • Be proficient to integrate various biochemical, biophysical and structure analysis tools for drug target characterization.

  • A good team-player, willing to collaborate, actively communicate, eagerly learn new technologies and share knowledge.

  • Have meticulous and rigorous altitude towards foundation of the science hypothesis and proven of hypothesis through carefully designed experiments.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

(高级)研究员,细胞生物学  

Key Responsibilities

  • Apply biology and cellular pharmacology knowledge and skills to design and execute biochemical and in vitro cellular experiments involving the evaluation of small molecule modulators.

  • Develop and validate a variety of cellular assays to understand the target of interest and characterize small molecule inhibitors/activators.

  • Establish robust screening assays to support medicinal chemistry lead optimization programs and contribute to DC (development candidate) identification for ongoing drug discovery projects.

  • Design and manage in vivo pre-clinical pharmacokinetics, pharmacodynamics, and toxicity studies.

  • Coach and develop research associate/junior scientist in experimental design, data management and analysis.

  • Proactively investigate new or different technologies, methods, and service providers to ensure our work is being done in a scientifically sound, efficient, and reasonable way.

  • Bring forward innovative ideas, novel translational animal models and advanced technologies to support team goals.

  • Maintain and routinely employ in-depth knowledge of project-related scientific literature


Minimum Requirements

  • PhD in Biology, physiology, pathology or pharmacology with relevant postdoctoral experience and at least 3 years biotech/pharma working experiences.

  • Extensive experience in creating, developing, and running cellular assays; engineering cell lines to express or knock-down genes of interest, and interrogating cellular signal transduction pathways.

  • Experience with flow cytometry and general molecular biological techniques including q-PCR, ELISA, MSD and Western Blot etc.

  • Strong background in designing in vivo animal studies.

  • Strong knowledge of cell cycle arrest, apoptosis, and senescence

  • Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.

  • Committed to staying current with the latest scientific breakthroughs in the targeted oncology field from target identification through human clinical trials.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

资深研究员及以上,细胞生物学  

Key Responsibilities

  • Create, develop and validate quantitative mammalian cellular assays to address the project team’s mechanistic and functional needs.

  • Establish robust screening assays to support medicinal chemistry lead optimization programs.

  • Design and manage in vivo pre-clinical pharmacokinetics, pharmacodynamics, and toxicity studies.

  • Design and manage physiological experiments in translational disease models to test efficacy and mechanism of action of novel clinical candidates.

  • Establish PK/PD relationships, demonstrating proof-of-concept, enabling candidate selection and delivering data for clinical dose predictions in preclinical in vivo experiments.

  • Establish pharmacology strategy in alignment with company pipeline objectives.

  • Proactively investigate new or different technologies, methods, and service providers to ensure our work is being done in a scientifically sound, efficient, and reasonable way

  • Bring forward innovative ideas, novel translational animal models and advanced technologies to support team goals.

  • Identify, evaluate, and manage vendors for outsourced services and studies.

  • Prepare reports for internal and external purposes including regulatory submissions.

  • Participate and lead project-based and technical team meetings to identify and solve problems, guide work towards project goals, communicate on-going work and progress, and plan forward thinking strategies.

  • Develop and continually advance one’s knowledge base on the molecular pathways being targeted by discovery and development research programs.

  • Identify opportunities and develop ideas to enhance and accelerate business processes.

  • Cultivates cross-functional relationships with project teams, translational medicine, biomarker teams, and disease-specific working groups to deliver novel targets, biomarkers and drug candidates.

  • Responsible for achieving pipeline goals by managing resource allocation and oversight of progress.

  • Present scientific accomplishments internally and externally to the scientific community and discussed with key opinion leaders.

  • Responsible for career development of team of diverse scientists, contribute to talent strategy and provide mentorship to group.


Minimum Requirements

  • PhD in Biology, physiology, pathology or pharmacology with relevant postdoctoral experience and at least 5 years biotech/pharma working experiences.

  • Extensive experience in creating, developing, and running cellular assays; engineering cell lines to express or knock-down genes of interest, and interrogating cellular signal transduction pathways.

  • Experience with flow cytometry and general molecular biological techniques including q-PCR, ELISA, MSD and Western Blot etc.

  • Strong background in designing in vivo animal studies.

  • Strong knowledge of cell cycle arrest, apoptosis, and senescence.

  • Experience in oncology and knowledge p53 signaling pathway is a plus.

  • Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.

  • Committed to staying current with the latest scientific breakthroughs in the targeted oncology field from target identification through human clinical trials.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

资深研究员及以上,微生物学家及项目经理  

Key Responsibilities

  • Lead drug development team/projects of anti-TB and other infectious disease areas in discovery to preclinical stages to reach critical G0/NoGo decisions, milestones and deliverable goals.

  • Participate and play a key role in disease biology for strategy and plan set up, collaboration with global partners, and evaluation of external opportunities.

  • Work closely with medicinal chemistry, structural biology, and DMPK teams to identify and promote promising hits through discovery and development stages.

  • Plan and drive all microbiology studies to meet anti-TB drug stage criteria.

  • Initiate, facilitate, and organize domestic and international collaborations with academic and industrial partners.

  • Develop written reports and oral presentations for monthly and quarterly meetings and annual reports.

  • Present findings in domestic and international meetings and publish on scientific journals.


Minimum Requirements

  • Have a Ph.D. in microbiology/bacteriology and/or molecular biology with a minimum 5 to 10 years working experiences in drug discovery and development.

  • Experiences in pharmaceutical industry or CRO in the field of antibacterial drug R&D is preferred. The experiences in leading project team in industry is highly appreciated.

  • Have a broad and deep understandings of cutting-edge technologies and challenges in anti-microbial, particularly TB, drug discovery and development.

  • Have oral and written English communication skills to meet the requirement of this position.

  • Be capable of working in and contributing to an interactive and multidisciplinary team environment.

  • Possess excellent team management skills and the ability to interact effectively with an international network of laboratories and disease experts.

  • Be meticulous in maintaining lab notebooks and data files.

  • The applicants should demonstrate a proven track record of scientific achievements and creative problem-solving skills.

  • Those with in-depth knowledge in genome editing, chemical biology, systems biology, parasite genomics, biomarker discovery, host immunity, vector biology, or in vivo animal model studies will be preferred.

  • Hands-on experiences in vitro cell culture, microscopy, flow cytometry, and molecular biology are ideal, but not required.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

研究员/资深研究员,疾病生物学  

Key Responsibilities

  • Responsible for genetic manipulation with Mycobacterium and/or other bacterial pathogens, developing phenotypic assays and HTS for antibacterial.

  • To identify antibacterial drug target, analyze the mode-of-action of small molecule, and bacterial strain typing and genome sequence analysis.

  • Develop knowledge to strengthen the medical and pharmaceutical aspects of the projects.

  • Facilitate both internal and external collaborations, and provide scientific expertise across functions/teams.


Minimum Requirements

  • PhD degree in microbiology or the related biological sciences with proven record of accomplishment. Experience in Mycobacterium model organisms (M. tuberculosis, M. smegmatis, M. bovis BCG, etc.) is highly appreciated. Industrial or CRO experience in whole bacterial cell screen against small molecule library is preferred. Animal model and/or pharmacology experience would be a plus.

  • Have at least five years of experience and in-depth understanding of general microbiology, bacterial genetics, and microbial biochemistry.

  • Highly self-motivated, and be willing to work diligently in a collaborative and dynamic team environment. Strong oral and written capability in English.

  • Result driven, multi-task, communicate clearly and present in a professional manner.

  • Scientific integrity is a must, candidate should be professional in maintaining lab notebooks and electronic files.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

研究员/资深研究员(生物化学家 & 药物学家),疾病生物学  

主要职责

  • 研究小分子抗生素化合物的作用机理。

  • 用系统生物学和各类组学的方法确立药物靶点并进行验证。

  • 开发可用于药物筛选的分子与生化反应体系,特别是细菌基因的转录翻译过程, 和细菌的细胞壁合成与能量代谢途径。

  • 开发实验动物细菌感染模型用于靶点和小分子药物的研究。


任职要求

  • 已取得分子生物化学,微生物遗传,医学微生物,动物兽医或相关生物科学硕士或博士学位,具有0-6年相关经历。

  • 具有研究细菌传染病和实验动物模型的科研经历,和有优良的数据分析能力的申请人会被优先考虑。

  • 具备良好的团队合作精神,优秀的协作能力和英文沟通能力。

  • 应聘者必须具备严谨的科研素养,并能严格对实验记录和电子文档进行归档整理。


工作地

北京市海淀区永泰庄北路1号


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org


* 该职位享有“人才招募推荐计划”。

各级别研究员,生物信息  

Key Responsibilities

  • Be able to handle large data sets including DNA/RNA seq, NGS assembly, omics data such as proteomics, PDB, etc.

  • Perform sequence/omics data analysis etc to help with genome annotation and functional/metabolic pathway analysis. Relevant areas include (but are not limited to) metagenomics, metabolomics, proteomics and other omics

  • Perform information search and collection for relevant targets or projects in publication, conference, communication and any other resources

  • Assist target identification, selection and validation

  • Help with mutation and drug resistance analysis

  • Develop novel methodologies/workflow by combining bioinformatics, AI and physics-based approaches to help lower resistance rate

  • Refine available or develop novel methods for drug target identification

  • Work closely with project teams to understand the requirement and help interpret data and results


Minimum Requirements

  • Master or PhD degree in Bioinformatics/Computational biology with a record of demonstrated productivity.

  • Experience in drug discovery is a plus

  • Coding experience is preferred

  • The candidate must have good communication skills to work in a collaborative team environment. Oral and written skills in English are preferred.

  • Scientific integrity is a must, candidate should be professional in maintaining lab notebooks and electronic files.


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

大数据科学家/工程师  

Key Responsibilities

  • Write reusable, testable, and efficient code based on project requirement and existing source code

  • Implement in-house big data application involving data integration, data mining and natural language processing based on pre-designed architecture

  • Implement Front and Back-end of AI applications based on pre-designed algorithm and architecture.


Minimum Requirements

  • Strong understanding and coding experience of Python is required, experience with other object-oriented language such as Java, C++ etc., is a plus.

  • Good understanding of data structure, able to process and integrate multiple structured/unstructured data sources and databases into one data system, fluent in SQL or similar data processing language.

  • Good understanding of relational database (SQL based) and big data (Hadoop/Spark) architecture and able to create database schemas and perform routine database operations based pre-designed protocol.

  • Majored in computer science, software engineering, mathematics, electric engineering or similar disciplines. Having a B.S. or M.S. degree is a plus

  • A good understanding of Machine learning/Deep learning and Natural Language Processing algorithms is a plus

  • Experience with Deep Learning framework, e.g. pytorch, tensorflow is a plus

  • Experience with pharmaceutical industry software and database development is a plus


Location

Beijing, China


About Us

Global Health Drug Discovery Institute (GHDDI) in Beijing is jointly founded by the Bill & Melinda Gates Foundation, Tsinghua University and Beijing Municipal Government. GHDDI aims to build a transformative drug discovery and translational platform with advanced biomedical research and development capabilities. It is an independent, not-for-profit organization with a broad interest in addressing global health concerns, regardless of financial incentives, and intends to focus its efforts on tackling the world’s most pressing disease challenges faced by many developing countries.

GHDDI provides comprehensive compensation and benefit packages as well as a growing, robust and diverse work environment for motivated and talented individuals who share GHDDI’s vision, and are committed to making a difference in science and human healthcare.


Contact

If you are interested in these exciting opportunities at GHDDI, please submit your CV with a cover letter to career@ghddi.org


 * The position is eligible for "Employee Referral Program".

各级别研究员,人工智能/计算生物学  

主要职责

  • 利用人工智能探索小分子药物研发的新算法。

  • 建设一个多功能的人工智能技术平台用于帮助缩短药物研发的过程。

  • 利用数据挖掘和数据集成技术,建立一个具有连续扩展能力的内部综合数据库。

  • 将基于人工智能的新方法应用到机构内部药物研发项目上。


任职要求

  • 已经取得计算化学, 生物信息学, 计算机科学等相关学科的博士学位且成果优异。

  • 对机器学习和深度学习有基本的了解,有实践经验者将被优先考虑。

  • 对Python语言有很好的理解和编码经验,有其它编程语言的经验者优先

  • 有药物研发经验者优先考虑

  • 应聘者必须具备良好的沟通能力,并能在团队环境中协同工作。英语口语及书面表达能力优秀者将被优先考虑。

  • 应聘者必须具备严谨的科研素养,并能熟练的对实验记录和电子文档进行归档整理。


工作地

北京市海淀区永泰庄北路1号


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org


* 该职位享有“人才招募推荐计划”。

资深研究员及以上,药物化学部  

主要职责

  • 领导一个或多个小分子药物研发项目在靶点验证、先导阶段和优化阶段中的药物化学工作。

  • 与跨学科的核心研发团队成员协作,设计并实施研发项目发展战略,以推进项目成功取得高质量临床前候选化合物。

  • 独立从事药物分子设计与构效关系研究,以完成设定的项目目标;设计合成路线,并引领研究中心和外部合作伙伴公司的化学团队合成与鉴定候选药物。

  • 与计算化学团队紧密合作,设计基于结构的靶标分子。

  • 积极沟通项目的发展战略和关键问题,以做出合适的资源决策。

  • 与计算化学团队紧密合作,设计基于结构的靶标分子。

  • 管理和监督团队工作,并为团队成员提供科学指导和技术培训。

  • 与研究中心内部和外部的研究团队建立高效的沟通机制。


任职要求

  • 已取得化学或其他相关领域的博士学位。

  • 应聘者须具备五年以上在药物化学领域的工作经历;具有在制药/生物科技行业小分子药物研发的实践经验及临床前研发经验的应聘者将获得优先考虑。

  • 在小分子候选药物的临床前研发方面有着突出的个人与团队贡献,包括发表过高水平的学术论文,口头报告与专利申请等。

  • 具有优秀的有机化学背景和专业知识,以及包括新合成路线设计能力等高水平的合成技能。

  • 具有项目领导经验以及在小分子药物研发的各阶段制定战略和重要决策的能力。

  • 优秀的解决问题能力及人际沟通能力,能在团队环境中与机构其他的研发或管理人员高效协同工作。

  • 具有良好的领导或者与CRO的化学团队合作经验更佳。


工作地

北京市海淀区永泰庄北路1号


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。

GHDDI为员工提供合理薪酬、年假以及全面社保,并致力于创造一个充满活力、包容和多元化的工作环境,使个人拥有快速成长的发展空间和一份有趣、有价值、有使命感的事业!


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org。


* 该职位享有“人才招募推荐计划”。

研究员/资深研究员,计算化学部  

主要职责

  • 进行同源建模与改良。

  • 协助靶点验证。

  • 开展虚拟高通量筛选并对实验化合物进行优化排序。

  • 引导先导化合物的生成及优化。

  • 开发解决药物研发中重要且具有挑战性问题的新方法,支持计算机辅助药物研发工作。

  • 与药物化学家、结构生物学家及机构其他部门紧密协同工作。


任职要求

  • 已经取得计算化学博士学位且成果优异。

  • 至少具有1~3年的基于结构的药物设计经验,具有3年以上药厂工作经验的优先考虑。

  • 应聘者必须具备良好的沟通能力,并能在团队环境中协同工作。英语口语及书面表达能力优秀者将被优先考虑。

  • 应聘者必须具备严谨的科研素养,并能熟练的对实验记录和电子文档进行归档整理。


工作地

北京市海淀区永泰庄北路1号


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。

GHDDI为员工提供合理薪酬、年假以及全面社保,并致力于创造一个充满活力、包容和多元化的工作环境,使个人拥有快速成长的发展空间和一份有趣、有价值、有使命感的事业!


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org。


* 该职位享有“人才招募推荐计划”。

人工智能科学家/工程师  

Global Heath Drug Discovery Institute(GHDDI)的人工智能团队正在寻找在人工智能和数据科学领域具有丰富经验的算法研究人员及工程师。

  • 做为一个新成立的部门,AIDD(AI for Drug Discovery)旨在通过领先的人工智能技术来改进和加速药物的发现过程。

  • GHDDI致力于开发用于治疗发展中国家的重大疾病新型药物的创新方法。

  • 作为中国第一家国际性独立的非营利性研究机构,GHDDI也开创了中国在科学领域走向未来合作的道路。

  • 候选人将有机会通过技术手段促进全球健康的进步,让人们的生活更美好。

主要职责

  • 将深度学习方法(分类、回归、排序、推荐、图神经网络、半监督学习、强化学习和贝叶斯网络)应用于内部药物发现项目。

  • 探索用于发现小分子新药的基于AI的创新算法。

  • 构建加速新药发现的多功能辅助AI平台。


任职要求

  • 专业方向包括但不限于:计算机科学、电子信息、应用数学或相关专业,硕士以上学历,博士优先。

  • 至少在以下方面之一有深入的经验:机器学习、深度学习、计算机视觉、自然语言处理、知识图谱、计算化学、生物信息学。

  • 熟练使用以下编程语言:C或C++,Python。

  • 良好的团队合作和沟通能力。

  • 行动导向,良好的逻辑思考能力和发现、总结问题的能力。


如何从人群中脱颖而出

  • 良好的科研和论文发表经历。

  • 熟练使用以下深度学习框架之一:PyTorch、TensorFlow、Theano或Caffe / Caffe2。

  • 良好的英语口语和书面技能。

  • 有药物发现研发经验者优先。

工作地

北京市海淀区永泰庄北路1号


关于我们

全球健康药物研发中心(Global Health Drug Discovery Institute,简称“GHDDI”)是由清华大学和比尔及梅琳达·盖茨基金会发起,北京市科学技术委员会代表北京市人民政府联合出资支持下成立的一个独立运营、非营利性质的全球公共卫生与药物创新机构。中心关注全球健康问题,致力发展杰出的生物医药研究与开发能力,建设新药研发和转化的创新平台,为解决发展中国家面临的突出疾病挑战做出贡献。


联系我们

申请者请发送个人简历以及代表性论文清单至 career@ghddi.org


* 该职位享有“人才招募推荐计划”。